If the question is whether it is possible for the hilt to date to Muhammed Kanta's time, then the answer is Yes. The guard with quillons terminating in monster heads turned towards the blade existed in the Islamic world as early as the 14th-15th century and the hilt may have been exported to Egypt and from there all the way to Hausaland. This may have even happened before the Ottomans made it to North Africa.
If the questions is whether it is plausible, then things get more complex. The main problem is the lack of similar hilts we can compare it to. In fact the only example of a hilt made entirely of metal with this kind of guard and a pommel in the shape of a monster or lion head is the one on the nimcha, #67 in the "Gold and Damascus Steel" catalogue. Number 1005 in Buttin comes close, but it has a typical nimcha guard.
Hopefully there are other examples out there, but these are the ones I am aware of. A couple of examples are far from enough to establish any trends, but for what it is worth, Buttin dates 1005 as late 16th, early 17th century. Number 67 in "Gold and Damascus Steel" is dated as early to mid-17th century and that dating makes a lot of sense to me.
And then there is the blade on the "Sword of Kanta", which we cannot see in its entirety, but which we know is a European blade, most likely from Northern Italy and dates most likely to the 17th century as well. But the blade itself is not sufficient to provide dating, because as Bivar points out, it could have been paired with the hilt at a later point. Broadswords were preferred over sabers in the Sahel, but then there is another sword in Bivar, from the Emirate of Katsina's regalia, which as a 14th or 15th century Mameluke saber blade. Based on that we cannot dismiss Bivar's point - this may have originally been a saber with the hilt then transferred to a European straight blade.
Overall, it is more likely that this sword is from the 17th century, and belonged to one of Muhammed Kanta's successors, but there is a possibility that the hilt may indeed have been something he held and used.